Short‐term outcomes in infants with mild neonatal encephalopathy: a retrospective, observational study

Abstract Background Neonatal encephalopathy due to acute perinatal asphyxia is a major cause of brain damage. Moderate severe neonatal associated with high mortality and morbidity rates. However, the neurodevelopmental outcomes in neonates mild are unclear. The primary aim this single-center observational study was assess short-term term asphyxia. A secondary identify predictors poor prognosis by identifying characteristics these infants according their outcomes. Methods We retrospectively investigated all at Tokyo Metropolitan Children’s Medical Center from January 2014 December 2019. An abnormal outcome defined as any one following: seizures or electroencephalography, magnetic resonance imaging obtained within first 4 weeks life, neurological examination findings discharge. Results In total, 110 during period were screened 61 diagnosed encephalopathy. Eleven (18 %) had an outcome. median Thompson score admission significantly higher than those normal (5 [interquartile range, 4-5.5] vs. 2 1–3], p < 0.01). Receiver operating characteristic curve analysis showed that cutoff value sensitivity specificity (90.9 83.0 %, respectively) for prediction Conclusions 18 % outcome, such findings. may be useful predictor